Liquid Cyclodextrin vs Capsule Cyclodextrin

Our liquid delivery system, phytomulsionTech®, harnesses the power of hydroxypropyl-β-cyclodextrin (HPBCD) to maximise the potential of the bioactive nutrients of our supplements. Research has shown that when the bioactive nutrients of our supplements is combined with HPBCD, they are over 100 times more water-soluble than the bioactive nutrients alone ^[1].

phytomulsionTech® technology represents a groundbreaking advancement in bioactive nutrient absorption, transforming the effectiveness of bioactive nutrients within your body. By harnessing the power of HPBCD, known for its safety and efficacy, in combination with approved surfactants and emulsifiers in phytomulsionTech®, we've engineered a cyclodextrin liquid delivery system that maximises the benefits of bioactive nutrients. Specifically, phytomulsionTech® significantly amplifies the bioavailability of the bioactive nutrients of our supplements.

This innovative approach means that a daily intake of just 120 mg of ecdysterone, the bioactive nutrient in our Exercise Support Supplement, equates to an impressive 1,200 mg of bioavailability in your body, matching the high intake standards of Olympic athletes and bodybuilders who typically consume around 1,000 mg.

It means that once ingested, the bioactive nutrients dissolve much better, enhancing its absorption in your digestive system. This significantly improves how well and how quickly your body can use it. In fact, this advanced delivery method makes the bioactive nutrients in our supplements 10 times more bioavailable than standard forms ^[2]. By integrating this scientifically-backed HPBCD system into Phytasorb®, we ensure that you get a superior, more efficient supplement.

While other supplement companies are integrating cyclodextrin into their capsule products alongside ecdysterone, they overlook a crucial detail that sets our Phytasorb® technology apart. In these capsule products, ecdysterone and cyclodextrin are merely adjacent; they are not truly complexed together into a delivery system. In contrast, our Phytasorb® technology takes a more advanced approach by reacting ecdysterone with cyclodextrin, in our manufacturing facility, to create a pre-complexed liquid form, ensuring a more effective delivery system.

When bioactive nutrients (such as ecdysterone or turkesterone) are merely mixed with cyclodextrin in capsule form, some improvement in bioavailability is noted when compared to consuming these nutrients alone. However, this method falls short as the digestive process does not guarantee the complete complexation of these nutrients with cyclodextrin. Numerous variables within the human digestive system, such as the contents of the stomach and intestines, the time for capsule disintegration and dissolution, the stomach's acidity, and the presence of other lipids, can impede the perfect complexation of bioactive nutrients with cyclodextrin. Given these unpredictable factors, relying on the body's natural complexation process is not the most effective approach.

Recognising this, scientific studies prefer to pre-complex cyclodextrins with bioactive nutrients to ensure a uniform and controlled delivery, thereby avoiding inconsistent absorption rates. This meticulous process is precisely what our Phytasorb® embodies. Our liquid cyclodextrin complex-inclusion formula in our supplements mirror these scientific methodologies, ensuring that the bioacive nutrient is fully and effectively complexed with cyclodextrin. This guarantees enhanced absorption and bioavailability, offering a superior option compared to the bioacttive nutrient (such as ecdysterone or turkesterone) and cyclodextrin capsule combinations. With Phytasorb®, you are choosing a product that aligns with scientific standards, ensuring optimal potency and efficacy of supplement bioactive ingredient delivery.

1. Temirgaziyev BS, Kucakova K, Baizhigit YA, Jurasek M, Dzubak P, Hajduch M, et al. Bioavailability and structural study of 20-hydroxyecdysone complexes with cyclodextrins. Steroids. 2019;147:37-41. DOI: 10.1016/j.steroids.2018.11.007
2. Wang L, Li S, Cai H, Liu X, Feng T, Zhao X. Preparation and characterisation of ecdysterone/hydroxypropyl-Beta-cyclodextrin inclusion complex with enhanced oral and transdermal bioavailability. J Microencapsul. 2022;39(2):145-55. DOI: 10.1080/02652048.2022.2056251